I stumbled across Lion’s Mane mushroom when I was researching supplements that would repair the nerve injury I sustained after my mastectomy.
[For those readers who have not been following my blog: I woke up from my mastectomy only to discover that my left arm was paralysed and numb. I had a brachial plexus C5/C6/C7 nerve injury. Yep, bummer.]
Amongst the nerve repair and peripheral neuropathy supplements I researched were: earthworm extract (lumbricus), Acetyl-L-Carnitine, St. John’s Wort, Benfotiamine, Vitamin B12, and Lion’s Mane mushroom.
I found it difficult to get hold of earthworm extract. A supplement does exist from the US, containing lumbricus in combination with other herbs (as part of a TCM formula), and is primarily used by Alzheimer’s patients. I asked my TCM practitioner why there was no lumbricus for sale in the UK and he said that in the UK, it was illegal to sell TCM herbal formulas containing animal substances. And unfortunately I was too tender-hearted to start grinding up the earthworms in my garden!
So what’s the big deal about Lion’s Mane mushroom?
Here are just a few of the scientific studies on Lion Mane’s amazing ability to facilitate nerve repair, including the gold standard of double-blind placebo-controlled clinical trials:
- Functional Recovery Enhancement Following Injury to Rodent Peroneal Nerve by Lion’s Mane Mushroom, Hericium erinaceus – International Journal of Medicinal Mushrooms, DOI: 10.1615/IntJMedMushr.v11.i3.20, Kah-Hui Wong et.al. [skip this one if you’re squeamish as it required squashing the little paws of mice to induce a nerve injury]
- Hericenones and erinacines- stimulators of nerve growth factor (NGF) biosynthesis in Hericium erinaceus – Mycology: An International Journal on Fungal Biology, 1:2, 92-98 – Bing-Ji Ma et.al.
- Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. – Biomedical Research, 2010 Aug;31(4):231-7, Mayumi Nagano et. al.
- Nerve Growth Factor-Inducing Activity of Hericium erinaceus in 1321N1 Human Astrocytoma Cells”. Biological & Pharmaceutical Bulletin 31 (9): 1727–1732. doi:10.1248/bpb.31.1727. PMID 18758067
- Improving Effects of the Mushroom Yamabushitake (Hericium erinaceus) on Mild Cognitive Impairment- A Double-blind Placebo-controlled Clinical Trial – Phytotherapy Research 23 (3): 367–372. doi:10.1002/ptr.2634, Koichiro Mori et. al.
- Hericium erinaceus an edible mushroom with medicinal values – J Complement Integr Med. 2013; 10(1): 1–6, doi 10.1515/jcim-2013-0001, Md. Asaduzzaman Khan*, Mousumi Tania, Rui Liu and Mohammad Mijanur Rahman
As you can see, nerve repair includes not just peripheral nerves (of the limbs), but also of nerves in the brain, which makes it a definite contender for brain disorders such as Alzheimer’s and dementia.
How does it work?
There are two compounds, hericenones and erinacines, which seem to affect Nerve Growth Factor. The polysaccharides and beta-glucans have cytotoxic effects on gastric ulcers and the immune system.
My peripheral nerve surgeon had not heard of Lion’s Mane mushroom (much less lumbricus), and was very sceptical. His words were: there is no supplement that will heal a nerve injury.
So, did it work?
Hard to say. I was taking so many supplements. All I can say is that the nerve injury did get better, but only after further surgery (so in this sense, my peripheral nerve surgeon was correct). How large a role Lion’s Mane mushroom played is hard to gauge.
Lion’s Mane mushroom extract is a dark brown colour. When I opened the packet, there was a distinctive smell of shellfish. When I tasted it, it was a bit like eating powdered lobster shell, with hints of marmite/vegemite and strangely tasty.
Where can I get Lion’s Mane Mushroom?
I got my Lion’s Mane Mushroom extract from Hybrid Herbs. It was the best source I could find then. MRL also do a Lion’s Mane Mushroom, but it’s not an extract, just the powdered mycellium. I have to say I found the service from Hybrid Herbs very good. They even let me have a sample to try.
What’s exciting is that Oriveda have now got a very high potency Lion’s Mane mushroom extract. It’s 100% bioavailable and has more than 50% polysaccharides. I believe it’s one of the best on the market. You can buy Lion’s Mane mushroom from Oriveda here.
Better still, if you subscribe to Oriveda’s current newsletter, you will get a special 10% discount until their next newsletter.