Fulda 2013 conference #3: Master Amino Acid Pattern (MAP) and its special use in cancer (Prof. Dr. Maurizio Luca-Moretti)

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The Christmas Market at Fulda

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[This was the keynote speaker and the first presentation on the morning of the conference, on a subject that would be a recurring theme in other presentations.  Unfortunately, Peter and I  were driving from Frankfurt, and because of traffic congestion, arrived about 30 minutes from the end of the lecture.

My apologies therefore, that my notes are incomplete, and this post therefore does not do justice to Prof Luca-Moretti’s fascinating lecture.  If anyone has a recording of the lecture, please send it to me and I will be more than happy to fill in the gaps.  This post is an amalgamation of several information handouts to give the background to the MAP and to place the talk in its context.]

The Speaker:  Professor Doctor Luca-Moretti has a doctoral degree in medicine, and is former professor for clinical nutritionat St. Thomas University in Florida.  He was also scientific director, president and CEO of the International Nutritional Research Centre (INRC) in Coral Gables, Florida.  He is the discover of Master Amino Acid Pattern (“MAP”), and has published numerous scientific publications and received international awards for his discovery relating to MAP.

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My impression

Master Amino Acid Pattern (MAP) is a product that neither I, nor Peter had come across before.

Amino Acids are an essential part in building proteins in the body and in maintaining its functions and metabolism.

MAP, which contains eight essential amino acid building-blocks can be used to fill in the gaps in diets, or in people who have special nutritional needs and increased protein requirements.  These include athletes, bodybuilders, convalescents, children/adolescents and pregnant women, and also people who are unable to digest proteins properly.

I can see it as being useful also in the treatment of cancer as a metabolic disease (e.g. with the ketogenic diet).  It also allows cancer patients to maintain protein levels (and muscle mass and bodily functions) without creating high-levels of waste products that would stress an already compromised system, or increase the amount of acidity in the body.

End-stage cancer patients often have issues with getting enough nutrition, and MAP could offer a very effective way of dealing with cachexia, because of its bioavailability and high levels of absorbability.

One bottle of MAP (120 tablets) costs Euro55 (discounts for bulk orders).

I highly-recommend e-mailing Dr Reinwald and requesting the English version of the product leaflets (which are in German):  mail@drreinwald.de

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Background to and summary of Master Amino Acid Pattern (MAP)

Adapted from the product leaflet “Dr Reinwald Vital – MAP – Master Amino Acid Pattern” (see MAP-Product Info-Basic-E-Web (1) Copy)”:

  • What is the Master Amino Acid Pattern?  All living organisms, including human beings have a characteristic amino acid pattern, known as the Master Amino Acid Pattern.
  • Eight essential amino acids:  MAP provides the eight essential  amino acids:  L-Leucine, L-Valine, L-Isoleucine, L-Lysine, L-Phenylalanine, L-Threonine, L-Methionine and L-Tryptophan
  • Unique ratio:  These amino acids are supplied in a unique ratio and specific sequence.  This balance is significant.
  • Very little metabolic waste:  MAP achieves 99% Net Nitrogen Utilisation (NNU).  [This means that there is very little metabolic waste in the form of ammonia and urea, and minimal stress on the body to eliminate these wastes]
  • Superior protein synthesis:  Almost all the amino acids are used for protein synthesis and cell build-up (anabolic) of the body.  Just 1% of MAP is catabolic (break-down) compared with soya protein:  anabolic=17% and catabolic = 83%
  • Fast absorption:  MAP is completely absorbed in the small intestine within 23 minutes.  It does not require any proteolytic enzymes to process.  Normal nutritional protein takes 5 to 13 times longer to transition.
  • Very little waste:  MAP does not leave behind any digestive end-products
  • According to Prof. Dr Luca-Moretti, MAP supplies the highest protein nutritional value worldwide.

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Why are proteins so important?

From the leaflet “Dr Reinwald’s metabolic regulation”

Modern diets – insufficient nutrition and physical activity:  Modern diets tend to be predominantly filled with denatured, high-carbohydrate, low-protein and low-nutrient foods.  We need less high-energy food, and more food with vital nutrients like vitamins, essential fatty acids to optimise protein intake and take more physical activity.

What happens if we don’t get enough proteins:  If we don’t eat enough high-quality proteins we won’t lose weight or maintain weight in a healthy way.  If we suffer from protein deficiency, the body recognises this shortage as a hunger crisis, i.e. that there isn’t enough food out there, and reduces fat metabolism and lowers the metabolic rate, to save energy.  This also leads the body to store water and fat.  In the extreme cases, the body starts breaking down lean mass and this includes muscle and skin tissue, immune systems, hormones etc.  A protein deficiency leads to a weakened immune system and drop in the metabolic rate.  this causes yo-yo weight-loss/weight gain

We need more protein that is assumed:  Our ancestors had a higher portion of protein in their diets. The basic components of proteins (the amino acids) is the top priority for the human body.  If we eat too little protein, we still feel hungry, until the body has been supplied with the amount of protein required.  The modern tendency is to consume more calories than necessary in the form of fat and carbohydrates  – this causes protein undersupply and weight gain (as a result of food that is too high in energy and too low in nutrients).  This is known as the Protein Leverage Effect.

Problem of high protein levels – detoxification of waste by-products:  A higher supply of protein places a strain on the liver and kidneys because of the higher-level of nitrogen waste products (ammonia, urea) that are created when protein is broken down.  This places a strain on the detoxifying organs and also increases the acid level of our body.  This increases the use of our body’s bicarbonate blood buffering system through the urea cycle, and places the heart and circulatory system under increased strain.

MAP therefore avoids this problem without falling into the protein-deficiency trap.

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From Prof.  Dr Luca-Moretti’s lecture

Protein and cancer cells and healing – the dilemma

It is a fact that proteins nourish cancer cells.  Yet a cancer patient must consume a diet rich in good protein in order to thrive.  Yes, proteins nourish cancer cells, but if you don’t nourish them from the outside, they will nourish themselves from the inside.

Cancer cells nourish themselves 400 times faster.  They eat 400 times the amount of food normal cells eat.  They eat the amino acid pool in our bloodstream.

Our body catabolises (breaks down) four cells each time in order to use the nutrients of those four cells to survive.  However, in order to regenerate these cells, one of the cells needs to come from an outside source, i.e. protein.

After surgery, patients don’t eat the food in hospital because it is all the same (i.e. bland and unappealing), but the wound still heals … why is this possible?  Because the body uses the amino acid and food in the bloodstream.

The body uses amino acids and food in bloodstream, and cancer cells do the same. So you have to feed them in order that they do not consume the body’s amino acids.  If you don’t give them the nutrients, they will suck all the nutrients in the bloodstream.

So you nourish the good cells knowing that you will nourish the bad cells.

Q:  You mentioned that protein source from vegetables is only 17% so how is it possible that people can live to 102 years using normal nutrition?

A:  Protein in vegetables is mainly for the animals.

There is a huge range of good and bad nutrition, cf Third World countries where starving women can still get pregnant.  We are programmed to survive even in the presence of the lack of food.  Primitive human beings can go into hibernation.  We don’t do this anymore.

How many calories does a human being need to survive?  Zero.  In presence of lack of food, the metabolism can lower so that it is in hibernation and all we then need is 180 calories per day and we get these calories from the cells that are metabolised.

When you go to India and see any vegetarian in a gym, you will see the percentage of muscle is very low.  Pizza, bread, tomatoes are vegetable.  You go to any beach in Italy and you will see they don’t have a strong body with muscle – they have tiny bodies.  But Italians in the US, where they can eat a lot of steak, they have larger bodies.  Italian immigrants were short, but later generations were taller.  After 36 years, I can look at a person and know if they are malnourished or not.  As Jesus says:  you can recognise a tree from its fruit.

Q:  What about Myocarditis that only responds to some remedies?

A:  Protein synthesis is not just in muscles but also in neurotransmitters and all internal organs.  For people who are 100% vegetarians, an autopsy of the heart will shown that the heart weighs 40% less than a normal heart, and kidney and liver that are smaller than normal kidneys and livers.  The highest speed of cell renewal takes place in the heart (30 days to renew) and the liver (3 days all its cells are renewed).

There was an experiment using a liquid diet for weight loss programme – the patients died of heart problems.  

Q:  You talk about people losing weight, what about people losing 50-60kg overweight – what is your experience with them losing this weight in a short time?

A:  We have been running our weight-loss programme for 36 years.  Dr Luca-Moretti has 36 years’ of experience with overweight patients.  The real cause of obesity was discovered 32 years ago and no one else discovered it – it was so simple.  A person who is 80kg overweight – 80% of the weight is made up of water.  It is a problem of excessive water retention.  You need an excess of 15,000 calories if the overweight element is fat.  Diuretics were given to people over 80kg-120kg and the weight fell off in 2 days.

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